The Levels of Progesterone and Estradiol in the Blood Serum of Males Suffered from Diabetes Mellitus Type I and Type II, During the Disturbance of Reproductive Function

Temur Makharadze, Maka Gvalia, Nino Giorgobiani, Medea Tugushi, Khatuna Tsitsiashvili

The levels of progesterone and estradiol were defined in 42 patients, 18 of them were insulin-dependent (type I), 24 non-dependent (type II) patients. The results of our study has shown that: in the males suffered from either type I or type II diabetes mellitus with disturbance of reproductive function, the level of serum progesterone is elevated mostly in case of type II diabetes mellitus (78,3%), mainly in the patients more than 40 years old. There is correlation between the level of the progesterone and the duration of the disease (Type I - 10 years after the onset of the symptoms; Type II - 5 years after the onset of the symptoms). The elevation of estradiol level in the serum was revealed in the patients of both type of disease, but especially in case of type II diabetes mellitus. There is correlation between the elevation of the level of estradiol in the serum and the duration of the disease.

Keywords:   diabetes mellitus, reproductive function, progesterone, estradiol