Effectiveness of Aciclovir Treatment of Encephalities and Cerebral Dishaemia Caused by Viral Intracranial Infections

Ia Rukhadze, Manana Gordeziani, Nino Ninua

The purpose of the study was differential diagnosis and treatment of cerebral dishaemia and encephalitis, caused by intracranial viral infections. Neurovisual methods of investigates were used: CT, MRI and doplerography, IgM and IgG-antibody test in blood and cerebrospinal fluid, blood test for immunoglobulin examination by turbidimetric method and examination of lymphocytes. 39 patients were observed, 17-encephalitis and meningoencephalitis, 22-cerebral circulation disturbances (11-ischemic stroke, 5-intracerebral haematoma, 6-TIA). Data revealed IgM and IgG in all cases. Thus, antiviral and immunomodulative treatment was carried out together with vasoactive medication. Acyclovirotherapy is the method of chose, which should be used also in preventive purpose in poststroke period.

Keywords:   encephalitis, cerebral dishaemia, herpes virus, aciclovir