The Morphological Changes in Lymph Nodes during Clinical and Experimental Lymphadenopathy of Different Genesis

Zaza Avaliani, George Burkadze

Department of Pathological Anatomy, Tbilisi State Medical University, Georgia

The study was aimed to compare the most acute, morphologically and clinically diagnosed acute and chronic lymphadenopathy with morphological changes of lymphatic node obtained experimentally. Data obtained have showed that in various stages of the experiments a number of quantitative and structural changes of different regions of the lymphatic nodes with significant deviations of their cellular composition occurred. Similar data, which were observed in clinical cases, appeared to be in certain correlation with experimental results. It's concluded that clinical classifications of lymphadenopathies reflect the stereotypic response of the lymph node to the antigen action.

Keywords:   lymph node, antigen, changes