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Has been studied influence of plaferon on stimulation of restoration of renal functions in patients with only kidney urolithiasis. Total of 42 patients with urolithiasis of only kidney (control group - 23, and group, where plaferon was used - 19 patients) has been investigated. In the group where patients were subjected to plaferon injections, the creatinine clearance by the second week after operative intervention was increased (50±41ml/min) and reached statistically reliable difference compared to control data (38,3±4,2 ml/min; p<0,05). There was detected correlation between data of mean reabsorption of "osmotically free" water in each nephron and mass of functioning nephrons. This correlation in control group was expressed slightly and could not be assessed as positive. In both groups we did not determine correlation between excretive fraction of filtrated sodium and reabsorption of "osmotically free" water. Plaferon contributes to stimulation of restoration of renal function in patients with urolithiasis of only kidney after operative intervention and restoration of urine passage. Plaferon application in postoperative period revealed improvement of glomerular filtration and investigated parameters compared to control group. Plaferon should be used in patients with urolithiasis of only kidney with the purpose of stimulation of restoration of its function during postoperative period.
Keywords:
urolithiasis, only kidney, renal function, plaferon
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