Tocoferol Acetate during the Treatment of Primary Intrathoracic Pediatric Tuberculosis

Nana Tskhakaia, Nina Manjavidze, Natela Okujava

The patients of 1-14 age with intrathoracic Tuberculosis had treatment by tocoferol-acetate with the DOTS therapy as well, i.e. below 5 years - 50mg per day, for more than 5 years - 100mg per day. The control group included 50 patients. The treatment for them was accomplished by the standard method. The effectiveness of the treatment was defined by intensivity of sygnals that are characteristic for blood's electroparamagnetic centers oxidation process. According to the research, it was clarified, that the tocoferol acetate dicreases the disbalance between pro- and antioxidant systems during primary pediatric intrathoracic tuberculosis and have antioxidant treatment effect.

Keywords:  tocoferol acetate, children, tuberculosis, oxidative processes