Osteogenesis and Its Stimulation During Surgical Treatment of Odontogenic Cysts of the Jaw

Nunu Khetsuriani 

The present work was aimed to elaborate optimal approaches of treatment stimulating osteogenesis in patients with odontogenic cysts subjected to cystectomy, and thereby enlarge the number of indications of cyistectomy and osteostimulation of bony defects that have been left after operation. With this purpose, paste-like mixture of vitamin D3 (cholecalciferol) and sterile powder of egg's shell have been suggested. Experiments have been carried out on rats and patients with odontogenic cysts using the general morphological investigation, immunohistochemistry and cytophotometry: In all cases of surgical treatment of odontogenic cysts, the good functional effects, without complications and recurrences have been achieved. Two to three months later with the use of X-ray control, reduction tendency in cysts’ cavities was detected. Process of osteogenesis was accelerated markedly. Ussually, if it takes one to three years, in our case mentioned period was approximately reduced to six month. Has been stated that suggested drug reveals stimulating effect activating the processes of regeneration.

Keywords:  vitamin D3, cholecalciferol, powder of egg's shell, odontogenic cyst, cistectomy, osteostimulation