Clinical - Immunological Aspects of the Effectiveness of "Unguentum Rhodopesum 5,0%" during the Herpetic Stomatitis

Natia Nizharadze, Boris Korsantia, Nutsa Chipashvili, Ketevan Shalashvili

Has been studied effect of the preparation "Unguentum Rhodopesum 5,0%" on the immune competency of patients with stomatological herpes. Recurrence of herpes was characterized by decrease in all immunological parameters, the dynamics of which was less depended on the gravity of the disease process. In case of etiotropic therapy (aciklovir) the tendency of improvement of these data was observed, however without normalization. In case of treatment with "Unguentum Rhodopesum 5,0%", the more active dynamics of investigated parameters was expressed, than in the previous group. Significantly were improved indices of interferon and phagocytosis. Along with that, the strong correlation between immunological homeostasis and treatment results (rate of symptoms arrest and duration of remission). Has been proved and suggested recommendation for "Unguentum Rhodopesum 5,0%" application in case of stomatological herpes.

Keywords:  unguentum rhodopesum, herpes simplex, stomatitis, aciklovir