Cyclosporine and Clinical-Immunological Indices of Atopic Dermatitis Demodecosis

Tamara Ebanoidze, Alexandre Katsitadze

Department of Dermatology and Venerology, Tbilisi State Medical University, 
4 Constitution Street, T:(99532)959766 Tbilisi, Georgia

Treatment of atopic dermatitis is a most challenging problem of dermatology. Essential role is allocated to immunotropic drugs in particularly severe cases. The aim of the work was to evaluate clinical and immunological parameters of atopic dermatitis during the treatment with cyclosporine. Observations involved 17 patients of both sexes, aged over 20 and suffering a severe form of atopic dermatitis, which resisted methods of traditional treatment. They were prescribed two receipts of cyclosporine daily, maximum dosage 2 or 5 mg/kg per day (200-400mg daily). This work showed that treatment of severe cases of atopic dermatitis with cyclosporine leads to remarkable decrease of the signs and symptoms of the disease. No side-effects or complications have been noticed while using the prescribed dosage of the medicine. Cyclosporine may be recommended as a method of a choice, in case of severe atopic dermatitis.

Keywords:  cyclosporine, atopic dermatitis