Changes of Immune Response in Critical Situations after Treatment-protective Anesthesia

Archil Iashvili, Zurab Kheladze

Department of Anesthesia, Critical Care and Catastrophe Medicine, Tbilisi State Medical University, Georgia

Anesthetic agents suppress the body immune status in critical condition, which can reveal itself in complicated forms like allergy, infections and etc. Immunological parameters were studied in 60 patients. 20 patients were not treated with treatment-protective anesthesia (I group). Second group - 20 patients, who were treated with treatment-protective anesthesia Dormikum (24-72 hours with the doze of 0.03-0,1 m.k.g/k.gh). The other 20 patients - the third group, who were treated with treatment-protective anesthesia Tiopental Natria (24-72 hours with the doze of 4-8 m.kg/kgh.) According to the results of the analysis we can establish that there were changes in the immune status of all patients, but Midazolan (Dormikum) has minimal immunosuppressive qualities than Tiopental Natria.

Keywords:  immunosuppression, treatment-protective complications, critical situations