Comparative analysis of cytogenetic effects of red (0,63 mkm) and infrared (0,85 mkm) Low Intensity Lasers

Gvantsa Kharaishvili, Anna Gogelia

Genetic Department of Clinical and Experimental Medicine Institute of Tbilisi State Medical University, Georgia

High therapeutic efficacy and wide-spread usage of Low-intensity Lasers made it interesting to investigate their cytogenetic effects. For this purpose white laboratory mice were irradiated by submaximal dozes of red (0,63 mkm) and infrared (0,85 mkm) low intensity lasers and their cytogenetic effects on bone marrow cells were investigated microscopically. It is ascertained that submaximal dozes of both (red and infrared) Low intensity Laser Irradiation (LILI) shows mutagenic influence on chromosome apparatus of laboratory animals and is directly connected with the number of session and exposition, but aberration frequency is relatively low for red laser (rl): 10 minute red laser irradiation during 5 days doesn't change the number of aberration in comparison by the disorder of cell cycle or blockage of nucleic acid repair process.

Keywords:  Low Intensity Laser, chromosome aberrations, bone marrow