The Use of IRS 19 During Respiratory Tract Infections in Atopic Children

Ekaterine Chkhartishvili*, Lia Zhorzholiani**, Rusudan Karseladze**,
Nino Gelovani**

*Children's Clinical Hospital #1, Tbilisi, Georgia; 
**Scientific-research Institute of Pediatrics, Tbilisi, Georgia

The ecosystem of the bacterial flora in nasopharynx is the reservoir for bacterial pathogens involved in respiratory tract infection, bacteremia and meningitis. Respiratory infections are the third leading cause of death worldwide and are a priority for vaccine development. The aim of our study was: 1. to reveal some bacterial strains in nasopharyngeal flora during asthma-like symptoms accompanied other respiratory tract diseases in atopic children and, 2. to assess effectiveness of IRS 19 in complex treatment, probably, as a preventive agent against recurrent respiratory tract infections. Microbiological technology specific for microbial and fungal flora for nasopharyngeal smear culture techniques was used. On the basis of the scientific-research reports and on the results of our study, we can suggest that topical vaccines (microbial lysates) might have positive influence on nasopharyngeal flora or/and respiratory tract mucosal microbial environment.

Keywords:  respiratory tract disease, nasopharynx, bacterial flora, topical vaccine