The pathogenic treatment of diabetic peripheral neuropathy in patients with type 2 diabetes mellitus

Lali Nikoleishvili, Ramaz Kurashvili, Nana Khachapuridze, Nana Kvirkvelia

Georgian Diabetes Center, Tbilisi, Georgia

The study was conducted on 61 patients with Type 2 Diabetes Mellitus diagnosed the Distal Symmetrical Polyneuropathy (DSP). 31 patients from the study group were administered Thiogamma by i.v. route for first 3 weeks, followed by 600 mg orally for 4 weeks. 30 patients composed the control group. Follow-up was conducted in all patients. According to study data, Thiogamma therapy results in positive dynamics of DSP signs and symptoms, with improvement of reflexes and ENMG figures, indicating on better nerve function. Besides, the drug is positively effecting on carbohydrate metabolism. According to all above-mentioned, the Thiogamma could be widely used in treatment approach of the DPN in patients with Type 2 Diabetes Mellitus.

Keywords:  type 2 diabetes mellitus, diabetic neuropathy, treatment, alpha-lipoic acid