Oxidative stress in respiratory failure in pediatric patients

Nestan Abdushelishvili, Manana Giorgobiani, Irina Tsirkvadze

Department of Pediatric Surgery of Tbilisi State Medical University, Georgia

Acute respiratory failure is the frequent cause of patient admission to intensive care unit, or it is common complication of severe pathological conditions. Most patients with acute respiratory failure, who experience hypoxia, need supplemental oxygen in high concentrations. The goal of our research was to study the status of oxidative stress and efficiency of treatment with supplemental oxygen in pediatric patients with acute respiratory failure. The results of the research showed, that use of supplemental oxygen, especially in long-term treatment can aggravate oxidative stress with further damage to body tissues.

Keywords:  oxidative stress, respiratory failure, hypoxia