Evaluation of morbidity risk in school age children living under arsenic influence conditions and significance of micronuclei assays

Marina Gagoshidze, Marina Antelava, Ala Zedginidze, Nino Manjavidze, Lali Aladashvili, Ia Taboridze

Department of Pediatrics, Department of Hematology, Tbilisi State Medical University, Georgia;
Guduschauri National Medical Center, Tbilisi, Georgia

It has been studied morbidity structure of school age children living in Lukhuni gorge under arsenic influence. By comparing with control are documented authentically high frequency of doctoral visits and acute respiratory infections incidence. To confirm the arsenic influence we have determined micronuclei (MN) level in buccal exfoliation cells that reflects genetic changes. It is shown, that MN number correlates with arsenic concentration in environment. Has been reached authentic correlation between MN level and morbidity with acute respiratory infections.

Keywords:  ecology, arsenic, micronuclei, children’ health