Clinical-dopplerographic correlations of brain's hypoxic-ischemic injury in newborns

George Natriashvili, Nana khachapuridze, Nana Kapanadze, Nana Geladze, Givi Tukhashvili

Department of Child Neurology, Tbilisi State Medical University, Georgia

Hypoxic-ischemic encephalopathy encompasses a spectrum of neuropathologic and neurologic features that comprise a major portion of neonatal neurology. Hypoxic causes deep metabolic, cerebrovascular and brain’s organic disorders which are the reasons of severe neurological disturbance. The aim of our study was to determine the injurious affect of hypoxic-ischemic factors on the newborns brain, the correlations of clinical-dopplerografic patterns and prognosing CNS disorders. We have observed 198 full-term neonates by clinical-dopplerografically. The ultrasonic investigation was produced on the devices of "SIEMENS SONOLINE ELEGRA" and "LOGIC 700". Katamnestic period covered 1,5-2 years. Conclusion: 1)The decreased parameter of PI pulsatility index presents the high risk of development of brain hypoxic-ischemic injury. 2)Stable dopplerografic pathological patterns indicate severity of brain injury and poor prognoses. 3)Color flow mapping represents the high effective method for estimation the degree of brain's hypoxic-ischemic injury and prognosing the course of disease.

Keywords:  hypoxic-ischemic encephalopathy, pulsatility index, doppler, newborn