Prognostic value of glutatione-s-transferase during medicamentous treatment of advanced lung cancer

Marina Lortkipanidze, Dali Pirtskhalaishvili, Revaz Gagua

A.Gvamichava Oncology National Center, Tbilisi, Georgia

Has been studied glutatione-s-transferase as prognostic factor at medicamentous treatment of advanced lung cancer. Has been stated the level of glutatione-s-transferase in healthy individuals’ blood that ranges widely from 41 to 1,13 nmol/min/ml. Has been revealed correlation between glutatione-s-transferase activity and efficacy of carried out treatment. Treatment is less effective at high concentration of the above-mentioned marker in blood; discrimination level of glutatione-s-transferase in patients with lung cancer is 1,5 nmol/min/ml; On the basis of received data, detection of DST in blood serum of patints with advanced lung cancer is recomended for prognostic evaluation of cancer’s sensitivity to medicamentous treatment.

Keywords:  lung cancer, chemotherapy, prognostic factor